Understanding Genital and Perianal Warts

Genital and perianal warts are small growths that appear on the genitals or near the anus. Any sexually active person can get genital or perianal warts regardless of age, race, social class, or sexual preference.

Genital and perianal warts are caused by a virus called human papillomavirus (HPV). You can get genital and perianal warts through sexual contact with someone who has HPV. HPV is more common than any other sexually transmitted disease.1 If you have sex with an HPV-infected person even once, you have a 60% chance of getting genital warts.2

In women, warts can grow on the vulva, walls of the vagina, cervix, area between the genitals, or anus. In men, genital warts can grow on the penis, scrotum, or anus. You can also get warts in your mouth or throat if you have oral sex with someone who is infected.1

If you have genital and/or perianal warts, you may notice1,2:

  • Small, flesh-colored or gray swellings in your genital or anal area
  • Several warts close together that take on a cauliflower-like shape
  • Itching or discomfort in your genital or anal area
  • Bleeding when you have sexual intercourse

But sometimes genital warts do not cause any symptoms.1 Warts can grow and cause other problems. You may infect your partner if you are sexually active, or you may infect your baby if you are pregnant.1 Only a doctor can tell you for sure whether you have genital and/or perianal warts.

If you think you have warts or have been exposed to HPV, see your doctor.

Talking to Your Doctor About Treating Genital and Perianal Warts

Currently, there is no treatment for HPV, but there are several treatment options for genital and perianal warts.1 When choosing a treatment for you, your doctor will consider the number of warts, their specific location, and other factors. The 2 methods of treatment are doctor applied and patient applied.1,2

A doctor can use both surgical and nonsurgical treatments to remove warts.2 Patient-applied treatments, such as VEREGEN® (sinecatechins) Ointment, 15%, are prescription medicines for use at home.3

You should talk to your doctor about the treatment options for external genital and perianal warts.

Following is a list of questions that can help you talk with your doctor about external genital and perianal warts:

  • Should I tell my sexual partner that I have genital and/or perianal warts?
  • Are genital warts infectious?
  • Can genital and perianal warts come back again after treatment?
  • What is the risk of cervical or penile cancer if I have genital warts?
  • Is there a treatment option that will help me stay wart free longer?

Together you and your doctor can decide which treatment option is best for you.

Treating Genital and Perianal Warts With VEREGEN® (sinecatechins)

VEREGEN® is a medicine for the treatment of warts on the outside of the genitals and around the outside of the anus. VEREGEN® is the first and only prescription botanical treatment approved by the FDA. It is clinically proven to treat the warts you have and newly occurring warts3 (53.6% of patients achieved complete clearance). Please see Important Safety Information below.

There are many reasons to use VEREGEN®

  • VEREGEN® is made from a green tea leaf extract. It's a powerful, natural extract that works hard to clear up your genital and/or perianal warts.
  • In clinical trials, 12 weeks following treatment, nearly all patients who had complete clearance of warts remained clear (6.8% recurrence rate).4

For more information, visit Veregen.com

Important Product Safety Information

Do not use VEREGEN® Ointment, 15% if you are allergic to any ingredient in this product. Do not use VEREGEN® Ointment, 15% for warts in the vagina, cervix, or inside the anus. Avoid contact with your eyes, nostrils and mouth while ointment is on your finger(s).

Avoid use of VEREGEN® on open wounds. Do not expose skin that has been treated with VEREGEN® to the sunlight, sunlamps or tanning beds. Tell your doctor if you are using any other type of skin product on the area to be treated. Avoid sexual contact (genital, anal or oral) when VEREGEN® Ointment, 15% is on your genital or perianal skin. If you do choose to have sexual contact, you must wash off the ointment carefully before having protected sexual contact as the ointment may weaken condoms and vaginal diaphragms.

Be sure to tell the doctor if you have a weak immune system or if you are pregnant or nursing a baby. Avoid using this product in patients younger than 18 years of age, or for longer than 16 weeks, or for multiple treatment courses. If your warts do not go away or come back after treatment contact your doctor.

The most common adverse reactions that occurred in more than 20% of patients in studies with VEREGEN® were reactions of the skin and application site. These included reddening of the skin, itching, burning, pain or discomfort, skin ulcers, wearing down of the skin, swelling, hard spots, and rash with blisters.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088

References:
  1. Centers for Disease Control and Prevention. Genital HPV infection—CDC fact sheet. http://www.cdc.gov/std/HPV/STDFact-HPV.htm. Accessed November 3, 2008.
  2. eMedicineHealth. Genital warts (HPV infection). http://www.emedicinehealth.com/script/main/ art.asp?articlekey=58909&pf=3&page=1. Accessed June 24, 2008.
  3. VEREGEN® Ointment, 15% [Prescribing Information, 2008]. Melville, NY: PharmaDerm, a division of Fougera Pharmaceuticals Inc.
  4. Data on file, PharmaDerm.